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The June issue of the journal Effective Pharmacotherapy. Cardiology and Angiology No. 1, 2026 — Scientific Editor Professor A.S. Ryazanov

The latest issue of the journal Effective Pharmacotherapy. Cardiology and Angiology No. 1, 2026 (Issue No. 11, Vol. 22, 2026) has been published, devoted to pressing issues in the diagnosis, treatment, and prevention of cardiovascular diseases.

From the Scientific Editor

Dear Colleagues,

I am pleased to present the next issue of the journal Effective Pharmacotherapy. Cardiology and Angiology for 2026. As always, our publication focuses on the most relevant and challenging questions of diagnosis, treatment, and prevention of cardiovascular diseases that we encounter daily in real-world clinical practice.

The scope of this issue reflects the modern paradigm of cardiology: a shift from a narrowly specialized approach to a personalized, multidisciplinary patient management strategy that takes into account the full extent of the patient’s comorbid status. It is this perspective that enables us to enhance treatment efficacy and improve long-term prognosis.

The issue opens with clinical studies focused on the management of multimorbid patients. Pakhomova A.E. et al. analyze the specific aspects of diagnosing and treating iron deficiency anemia in patients with cardiovascular pathology—a problem requiring particular attention in outpatient practice. The study by I.M. Khapokhov and colleagues demonstrates the high efficacy of a standardized step-by-step algorithm for correcting dyslipidemia in patients with arterial hypertension, which has direct practical implications for overcoming therapeutic inertia. Worthy of special mention is the work that, using a retrospective cohort, demonstrates the potential of machine learning methods for personalized cardiovascular risk assessment in elderly and senile patients. This is a vivid example of how artificial intelligence technologies are gradually being integrated into routine clinical practice, improving the accuracy of prognostication and the evidence base for medical decisions.

In the Reviews section, we continue discussing key issues in modern cardiology. An analysis of barriers to effective lipid-lowering therapy in outpatient settings (A.S. Ryazanov et al.) offers practical algorithms and organizational solutions to increase the rate of achieving target low-density lipoprotein cholesterol levels. A review by M.V. Makarovskaya et al. summarizes current data on the cardioprotective potential of therapy in type 2 diabetes, highlighting drugs with proven effects on cardiovascular outcomes. An unusual perspective is presented in the work by E.S. Zhabina et al., dedicated to the circadian characteristics of ventricular arrhythmias—a factor that can complement the “portrait” of an arrhythmia and optimize chronotherapeutic strategy. This section concludes with a study by I.A. Lapik and K.M. Gapparova, presenting a pathogenetically grounded approach to the rehabilitation of patients with a combination of obesity, arterial hypertension, and bronchial asthma.

The Clinical Practice section, which invariably sparks lively interest, illustrates the complexity of managing patients in real life. We present a rare case of fulminant myocarditis associated with anti-RNA polymerase III antibodies (D.K. Arakelov et al.), with a detailed description of mechanical circulatory support algorithms. The next publication (Yu.V. Frolova et al.) demonstrates the successful experience of staged treatment of a cardio-oncology patient with colorectal cancer through interdisciplinary collaboration. The issue concludes with a clinical case discussion focused on the interaction of anticoagulant and antiepileptic therapy in a patient with post-stroke epilepsy (Yu.A. Chaichits et al.), serving as a reminder of the need for caution when co-prescribing medications.

I am confident that the presented materials will be useful to practicing physicians—cardiologists, internists, general practitioners—and will assist in making well-considered, pathogenetically grounded clinical decisions. I invite you to actively engage in professional discussion of the content, and I remind you that all journal materials are available electronically on the uMEDp.ru portal.